Combine all ingredients in a small sauce pan and set over medium heat. Simmer gently, lowering the heat if needed to prevent scorching, until combined and reduced until thickened a bit.
Sauce will also thicken as it cools. Taste for seasoning and add salt and pepper as necessary.
1 cup root beer
1 cup ketchup
1/4 cup orange juice
3 tbsps worcestershire sauce
2 tbsps brown sugar
1 tbsp molasses
1 tsp smoked paprika
1 tsp ground ginger
1 tsp garlic powder
1/2 tsp onion powder
1/2 tsp black pepper